eNOS

Genetic variants of the endothelial NO synthase gene (eNOS) may confer increased risk of sporadic congenital heart disease

K. Zhou, Wang, Y., Peng, W., Sun, J., Qing, Y. M., and Mo, X. M., Genetic variants of the endothelial NO synthase gene (eNOS) may confer increased risk of sporadic congenital heart disease, vol. 13, pp. 3805-3811, 2014.

The endothelial NO synthase (eNOS) enzyme is expressed during the early stages of cardiogenesis and plays an important role in normal heart development. Genetic variations of eNOS G894T have been shown to influence individual susceptibility to some phenotypes of congenital heart disease (CHD) in different populations. We conducted a case-control study comprised of 945 CHD patients and 972 non-CHD individuals in a Chinese population.

More severe clinical course of cardiovascular dysfunction in intensive care unit patients with the 894TT eNOS genotype

L. R. Fraga, Paludo, F. J. O., Bós, A. J. G., Ferraro, J. L. S., Dias, F. S., and Alho, C. S., More severe clinical course of cardiovascular dysfunction in intensive care unit patients with the 894TT eNOS genotype, vol. 12, pp. 562-568, 2013.

The endothelial nitric oxide synthase (eNOS) plays an important homeostatic role in the cardiovascular system (CVS) by maintaining appropriate blood pressure through production of nitric oxide. The 894TT genotype of 894G>T (Glu298Asp, rs1799983), a polymorphic variant of eNOS, has been associated with several vascular diseases. On the basis of this strong relationship, we monitored daily 585 critically ill adult patients according to their degree of CVS dysfunction and investigated their disease progression by the 894G>T genotype.

Association of eNOS gene polymorphisms with essential hypertension in the Han population in southwestern China

J. Li, Cun, Y., Tang, W. R., Wang, Y., Li, S. N., Ouyang, H. R., Wu, Y. R., Yu, H. J., and Xiao, C. J., Association of eNOS gene polymorphisms with essential hypertension in the Han population in southwestern China, vol. 10, pp. 2202-2212, 2011.

Endothelial nitric oxide synthase (eNOS) plays an important role in maintaining blood pressure homeostasis and vascular integrity. Polymorphisms in the eNOS gene have been found to be associated with hypertension in different human populations, including Northern and Southern Chinese Han populations.

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