Dengue virus RNA quantification through PCR: what is the best cost-effective approach?
“Dengue virus RNA quantification through PCR: what is the best cost-effective approach?”, Genetics and Molecular Research, vol. 22, no. 1, 2023.
, The surface of the dengue virus is composed of 180 copies of a multifunctional envelope glycoprotein that acts at several stages of viral infection. When the virus is in the endosome, these glycoproteins undergo major conformational rearrangements owing to the protonation of histidine side chains. This protonation allows for the formation of trimers, thereby triggering fusion between the viral and the host membranes.