FOXO3

Smoking, aging, and expression of proteins related to the FOXO3 signaling pathway in lung tissues

Y. M. Yuan, Luo, L., Guo, Z., Yang, M., Lin, Y. F., and Luo, C., Smoking, aging, and expression of proteins related to the FOXO3 signaling pathway in lung tissues, vol. 14, pp. 8547-8554, 2015.

We investigated the effects of smoking and aging on pro­teins involved in the forkhead box O3 (FOXO3) signaling pathways in the lungs. Sixteen senescence-accelerated mouse-resistant 1 (SAMR1) and senescence-accelerated mouse-prone 8 (SAMP8) mice at 3 months of age were divided into a normally aged, smoke-exposed group (4 SAMR1 mice), a normally aged, air-exposed group (4 SAMR1 mice), an aging-accelerated, smoke-exposed group (4 SAMP8 mice), and an aging-accelerated, air-exposed group (4 SAMP8 mice).

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