Gastric cancer

Propofol inhibits proliferation and accelerates apoptosis of human gastric cancer cells by regulation of microRNA-451 and MMP-2 expression

Z. Peng, Zhang, Y., Peng, Z., Zhang, Y., Peng, Z., and Zhang, Y., Propofol inhibits proliferation and accelerates apoptosis of human gastric cancer cells by regulation of microRNA-451 and MMP-2 expression, vol. 15, p. -, 2016.

Propofol is an extensively used intravenous anesthetic agent. The aim of the present study was to evaluate the effects of propofol on the behavior of human gastric cancer cells and the molecular mechanisms associated with this activity. The effects of propofol on proliferation and apoptosis in the SGC-7901 gastric cancer cell line were detected by an MTT assay and measurement of caspase-3 activity. The protein expression levels of matrix metalloproteinase-2 (MMP-2) were detected by western blotting.

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