Gene chip

PI3K-AKT pathway polymerase chain reaction (PCR) array analysis of epilepsy induced by type II focal cortical dysplasia

Y. X. Lin, Lin, K., Liu, X. X., Kang, D. Z., Ye, Z. X., Wang, X. F., Zheng, S. F., Yu, L. H., and Lin, Z. Y., PI3K-AKT pathway polymerase chain reaction (PCR) array analysis of epilepsy induced by type II focal cortical dysplasia, vol. 14, pp. 9994-10000, 2015.

The aims of this study were to observe the differential expression of PI3K-AKT pathway-related genes in seizure-inducing brain lesions in type II focal cortical dysplasia, and to explore the relationship between gene expression and histological changes in dysplastic foci and their epileptogenic mechanism. Typical lesions in brain tissue from three patients with epilepsy induced by type II focal cortical dysplasia were selected for analysis, along with normal brain tissue from two control group individuals.

Screening of differentially expressed genes in pathological scar tissues using expression microarray

L. P. Huang, Mao, Z., Zhang, L., Liu, X. X., Huang, C., and Jia, Z. S., Screening of differentially expressed genes in pathological scar tissues using expression microarray, vol. 14, pp. 10743-10751, 2015.

Pathological scar tissues and normal skin tissues were differentiated by screening for differentially expressed genes in pathologic scar tissues via gene expression microarray. The differentially expressed gene data was analyzed by gene ontology and pathway analyses. There were 5001 up- or down-regulated genes in 2-fold differentially expressed genes, 956 up- or down-regulated genes in 5-fold differentially expressed genes, and 114 up- or down-regulated genes in 20-fold differentially expressed genes.

Subscribe to Gene chip