Gene knockout mouse

Effect of transcription factor ZBTB20 on mouse pituitary development

Q. Dong, Chen, X. Y., and Li, G. M., Effect of transcription factor ZBTB20 on mouse pituitary development, vol. 14, pp. 17622-17629, 2015.

Pituitary, a critical component in the neuroendocrine system, plays an indispensable role in the regulation of body growth. The transcriptional factor ZBTB20 is widely expressed in brain tissues and participates in hippocampal development; however, the detailed molecular mechanism remains unknown. Therefore, the aim of this study was to investigate the effect of ZBTB20 on mouse pituitary development and related mechanisms in ZBTB20 gene knockout mice.

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