Genetic polymorphism

Environmental factors and polymorphisms of interleukin genes contribute to susceptibility to chronic periodontal disease

J. A. X. Manso, Hannum, R., Fortes, J. S., Duarte, S. S. M., da Cruz, A. S., Minasi, L. B., da Cruz, A. D., and da Silva, C. C., “Environmental factors and polymorphisms of interleukin genes contribute to susceptibility to chronic periodontal disease”, Genetics and Molecular Research, vol. 19, no. 3, 2020.

The T-allele of the SMARCA4 gene has an apparent protective effect against high levels of total and LDL cholesterol

H. A. G. B. Queiroz, Castro, F. S., Silva, A. M. T. C., Gomes, C. M., Costa, S. H. N., and da Cunha, L. C., “The T-allele of the SMARCA4 gene has an apparent protective effect against high levels of total and LDL cholesterol”, Genetics and Molecular Research, vol. 19, no. 1, 2020.

Genetic polymorphism at Interleukin-7 receptor gene at +510 position and its impact on pain and other symptoms among HIV and AIDS patients

T. C. Nangammbi, Moloro, G. T., and Samie, A., “Genetic polymorphism at Interleukin-7 receptor gene at +510 position and its impact on pain and other symptoms among HIV and AIDS patients”, Genetics and Molecular Research, vol. 18, no. 4, 2019.

Effect of genetic polymorphism of αS1- casein gene on qualitative and quantitative milk traits in native Bulgarian Rhodopean cattle breed

P. J Hristov, Teofanova, D., Georgieva, A., and Radoslavov, G., “Effect of genetic polymorphism of αS1- casein gene on qualitative and quantitative milk traits in native Bulgarian Rhodopean cattle breed”, Genetics and Molecular Research, vol. 17, no. 1, 2018.

AluYb8 insertion in the WNK1 gene is not associated with hypertension in a Russian Caucasian population

E. Akhmedova, Nikulina, S. Y., Salmina, A. B., Chernova, A., Bazanova, M., Ohapkina, A., Semenchukov, A., Maltese, P. E., Manara, E., and Bertelli, M., “AluYb8 insertion in the WNK1 gene is not associated with hypertension in a Russian Caucasian population”, Genetics and Molecular Research, vol. 16, no. 4, 2017.

Association between IL-1α rs17561 and IL-1β rs1143634 polymorphisms and periodontitis: a meta-analysis

W. T. Yin, Pan, Y. P., Lin, L., Yin, W. T., Pan, Y. P., and Lin, L., “Association between IL-1α rs17561 and IL-1β rs1143634 polymorphisms and periodontitis: a meta-analysis”, vol. 15, p. -, 2016.

Genetic variations in human interleukin-1 (IL-1) genes are known to be involved in inflammatory disorders. The rs17561 and rs1143634 polymorphisms of IL-1α and IL-1β, respectively, have been increasingly recognized as important regulators in the development of periodontitis. However, the existence of a specific association remains controversial. Therefore, we performed a meta-analysis to explore the relationship between IL-1 polymorphism and periodontitis risk.

NLRP3 rs35829419 polymorphism is associated with increased susceptibility to multiple diseases in humans

Q. Zhang, Fan, H. W., Zhang, J. Z., Wang, Y. M., and Xing, H. J., “NLRP3 rs35829419 polymorphism is associated with increased susceptibility to multiple diseases in humans”, vol. 14, pp. 13968-13980, 2015.

Using a meta-analysis framework, we investigated the association between the NLRP3 rs35829419 polymorphism and increased susceptibility to diverse diseases in humans. Relevant published studies were identified through a comprehensive and systematic electronic search, using the following scientific literature databases: Science Citation Index, the Cochrane Library, PubMed, Embase, CINAHL, Current Contents Index, Chinese Biomedical, the Chinese Journal Full-Text, and the Weipu Journal.

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