W. B. Cantero, Takahachi, N. A., Mauro, M. O., Pesarini, J. R., Rabacow, A. P. M., Antoniolli, A. C. M. B., and Oliveira, R. J.,
“Genomic lesions and colorectal carcinogenesis: the effects of protein-calorie restriction and inulin supplementation on deficiency statuses”, vol. 14, pp. 2422-2435, 2015.
The present study investigated the effects of restricting protein and calories and supplementation of inulin, a fiber comprising a linear type of polydisperse carbohydrates composed primarily of fructil-fructose bonds (β-(2→1), on the deficiency statuses of animals in which genomic lesion development and colorectal carcinogenesis had been induced. This experiment involved adult male Swiss mice (N = 11/group). The experimental groups were as follows: Negative Control (vehicle), Positive Control, 1,2-dimethylhydrazine (DMH), Inulin, and Associate.