Genotype

Establishment of reference sequences of hepatitis B virus genotype C subgenotypes

H. L. Zhu, Wang, C. T., Xia, J. B., Li, X., and Zhang, Z. H., Establishment of reference sequences of hepatitis B virus genotype C subgenotypes, vol. 14, pp. 16521-16534, 2015.

Hepatitis B virus genotype C (HBV/C) has the largest number of subgenotypes (C1-C16) that vary with geography and isolates. HBV/C prevails in Southeast Asia (C1, C5-C16), East Asia (C2), Oceania (C3), and Australia (C4). Suitable reference strains for different subgenotypes could greatly facilitate research into HBV/C, but unfortunately they are scarce. We retrieved 974 HBV/C full-length sequences from the GenBank database and subgenotyped them by phylogenetic analysis.

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