Growth trait

Investigation of TG gene variants and their effects on growth, carcass composition, and meat quality traits in Chinese steers

L. P. Zhang, Gan, Q. F., Hou, G. Y., Gao, H. J., Li, J. Y., and Xu, S. Z., “Investigation of TG gene variants and their effects on growth, carcass composition, and meat quality traits in Chinese steers”, vol. 14, pp. 5320-5326, 2015.

Thyroid hormones play an important role in regulating metabolism and can affect metabolism-related traits such as fat deposition. The thyroglobulin (TG) gene produces the precursor of thyroid hormones and has been proposed as a candidate gene for a quantitative trait locus with an effect on fat deposition. In this study, we identified 4 novel single nucleotide polymorphisms (SNPs) in the 5' flanking region of the TG gene using a DNA sequencing method.

Genomic cloning, expression, and single nucleotide polymorphism association analysis of the insulin-like androgenic gland hormone gene in the oriental river prawn (Macrobrachium nipponense)

F. J. Li, Jiang, F. W., Bai, H. K., Fu, H. T., Jin, S. B., Sun, S. M., Qiao, H., and Zhang, W. Y., “Genomic cloning, expression, and single nucleotide polymorphism association analysis of the insulin-like androgenic gland hormone gene in the oriental river prawn (Macrobrachium nipponense)”, vol. 14, pp. 5910-5921, 2015.

Increasing evidence suggests that the insulin-like andro­genic gland hormone (IAG) gene plays an important role in male sexual differentiation, metabolism, and growth in crustaceans. In the present study, we isolated the full-length genome sequence of IAG by genome walking based on the cDNA sequence in Macrobrachium nipponense. Four novel single nucleotide polymorphisms (SNPs) were studied, in­cluding 509G>T, 529G>T, 590A>T in intron 1, and 2226A>G in intron 2.

Associations between polymorphisms of the GFI1B gene and growth traits of indigenous Chinese goats

H. F. Cai, Chen, Z., and Luo, W. X., “Associations between polymorphisms of the GFI1B gene and growth traits of indigenous Chinese goats”, vol. 13, pp. 872-880, 2014.

This study aimed to investigate polymorphisms of the eighth exon in the GFI1B gene among three indigenous Chinese goat breeds (QianBei Ma goats, GuiZhou white goats, and GuiZhou black goats). Furthermore, association analysis was conducted between these polymorphisms and growth traits. Polymerase chain reaction-single strand conformation polymorphism (PCR-SSCP), direct DNA sequencing, and PCR-restricted fragment length polymorphism (RFLP) were applied to detect polymorphism sites, and a general linear model was used to analyze their association with growth traits.

Associated analysis of single nucleotide polymorphisms found on exon 3 of the IGF-1 gene with Tibetan miniature pig growth traits

M. Yue, Tian, Y. G., Wang, Y. J., Gu, Y., Bayaer, N., Hu, Q., and Gu, W. W., “Associated analysis of single nucleotide polymorphisms found on exon 3 of the IGF-1 gene with Tibetan miniature pig growth traits”, vol. 13, pp. 1263-1269, 2014.

The IGF-1 gene is an important regulating factor that has a growth-promoting effect on growth hormone. The IGF-1 gene promotes muscle cell differentiation in the muscle cell formation process. The IGF-1 gene also regulates the growth of skeletal muscle during skeletal muscle growth. In addition, the IGF-1 gene plays an important role in the formation of mammals and poultry embryos, and the process of postnatal growth. The IGF-1 gene has been implicated as a candidate gene for the regulation of pig growth traits.

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