Hardy-Weinberg equilibrium

Analysis of interleukin 19 serum levels and single nucleotide polymorphisms in systemic lupus erythematosus

J. R. Lin, Qin, H. H., Wang, Y., Liang, J., Xu, J. H., Lin, J. R., Qin, H. H., Wang, Y., Liang, J., and Xu, J. H., Analysis of interleukin 19 serum levels and single nucleotide polymorphisms in systemic lupus erythematosus, vol. 15, p. -, 2016.

Systemic lupus erythematosus (SLE) is an autoimmune connective tissue disease that affects multiple organs and diminishes a patients’ quality of life. It has been suggested that interleukin 19 (IL-19) is engaged in intercellular signal transduction, which is related to the immune response and the local inflammatory reaction. Single nucleotide polymorphisms (SNPs) have been used to explore the genetic basis underlying the pathogenesis of SLE. In this study, we investigated the potential correlation between the functional IL19 SNP rs2243188 and SLE.

Allele frequencies of combined DNA index system (CODIS) and non-CODIS short tandem repeat loci in Goiás, Central Brazil

R. G. Rodovalho, Santos, G. S., Cavalcanti, L. M., Moura, B. F. S. M., Rodrigues, E. L., Lima, P. R., Gigonzac, M. A. D., and Vieira, T. C., Allele frequencies of combined DNA index system (CODIS) and non-CODIS short tandem repeat loci in Goiás, Central Brazil, vol. 14, pp. 7310-7314, 2015.

In studies of human identification, obtaining a high standard of outcomes and satisfactory conclusions are directly related to the use of highly polymorphic molecular markers. In addition to the combined DNA index system (CODIS) group, it is also important to implement non-CODIS markers into the analysis, as they increase the power of discrimination. During the identification process, it is essential to consider the genetic variation among distinct groups of populations, as the allele frequencies are directly associated with the power of discrimination.

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