Helicobacter pylori eradication

Influence of CYP2C19 on Helicobacter pylori eradication in Brazilian patients with functional dyspepsia

D. D. Nabinger, Mazzoleni, L. E., Sander, G. B., Mazzoleni, F., Osório, M. C., Klein, M. G., Rech, T. F., L. da Silva, B., de Moraes, G. S., Cristovam, R. A., Nardelli, E. F., Francesconi, C. F. M., Simon, D., Nabinger, D. D., Mazzoleni, L. E., Sander, G. B., Mazzoleni, F., Osório, M. C., Klein, M. G., Rech, T. F., L. da Silva, B., de Moraes, G. S., Cristovam, R. A., Nardelli, E. F., Francesconi, C. F. M., and Simon, D., Influence of CYP2C19 on Helicobacter pylori eradication in Brazilian patients with functional dyspepsia, vol. 15, p. -, 2016.

The aim of this study was to examine the effect of polymorphisms in the cytochrome P450 (CYP) 2C19 gene (CYP2C19) on the Helicobacter pylori eradication rate in Brazilian patients with functional dyspepsia. Adults diagnosed with functional dyspepsia based on the ROME III criteria and infected with H. pylori were recruited to this study. The patients were subjected to gastrointestinal endoscopy and the H. pylori status was defined when both urease test and histopathology results were negative or positive.

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