Hepatitis A virus

Prevalence of hepatitis A viral RNA and antibodies among Chinese blood donors

P. Sun, Su, N., Lin, F. Z., Ma, L., Wang, H. J., Rong, X., Dai, Y. D., Li, J., Jian, Z. W., Tang, L. H., Xiao, W., and Li, C. Q., Prevalence of hepatitis A viral RNA and antibodies among Chinese blood donors, vol. 14, pp. 16431-16437, 2015.

Like other developing countries, China was reported to have a relatively high seroprevalence of anti-hepatitis A antibodies (anti-HAV). However, no studies have evaluated the prevalence of anti-HAV and HAV RNA among voluntary blood donors with or without elevated serum alanine transaminase (ALT) levels. Anti-HAV antibodies were detected using an enzyme-linked immunosorbent assay, and reverse transcription quantitative polymerase chain reaction was carried out for detection of HAV RNA.

Mapping codon usage in sequence regions flanking cleavage positions in the hepatitis A virus polyprotein

X. - X. Ma, Feng, Y. - P., Chen, L., Zhao, Y. - Q., Liu, J. - L., Guo, J. - Z., Guo, P. - H., Yang, J. - T., Lu, J. - X., Chen, S. - E., and Ma, Z. - R., Mapping codon usage in sequence regions flanking cleavage positions in the hepatitis A virus polyprotein, vol. 12, pp. 2306-2319, 2013.

To analyze the synonymous codon usage patterns of sequence regions flanking cleavage sites in the hepatitis A virus (HAV) polyprotein, the codon usage bias at codon positions and the synonymous codon usage in the target contexts of 30 virus strains were estimated by two simple methods that were based on the values for relative synonymous codon usage. In addition, the pattern of synonymous codon usage was compared between the genomic sequences in HAV and those of its human host.

Subscribe to Hepatitis A virus