Effects of Herceptin on circulating tumor cells in HER2 positive early breast cancer
, “Effects of Herceptin on circulating tumor cells in HER2 positive early breast cancer”, vol. 14, pp. 2099-2103, 2015.
The objective of this study was to determine the changes in peripheral blood circulating tumor cells in HER2-positive early breast cancer before and after Herceptin therapy, and to explore the effects of the HER2 gene and Herceptin on circulating tumor cells. CK19 mRNA expression in peripheral blood was evaluated by qRT-PCR as an index of circulating tumor cells in 15 cases of HER-2-positive breast cancer and 18 cases of HER2-negative breast cancer before, and after chemotherapy as well.
