Human papillomavirus

HPV genotyping and p16 expression in Xingu Indigenous Park, Brazil

V. G. Freitas, Focchi, G. R., Pereira, E. R., Levi, J. E., Speck, N. M. G., Ribalta, J. C., Freitas, V. G., Focchi, G. R., Pereira, E. R., Levi, J. E., Speck, N. M. G., and Ribalta, J. C., HPV genotyping and p16 expression in Xingu Indigenous Park, Brazil, vol. 15, p. -, 2016.

The association between high-risk human papillomavirus (HPV) genotypes and p16 expression in indigenous women from the Xingu Indigenous Park, Brazil, was unknown. This study evaluated p16 expression in women with a histological diagnosis of cervical intraepithelial neoplasia (CIN) 3 or higher and correlated this expression with HPV genotypes to determine possible discrepancies in the expression of this marker. We evaluated 37 previously collected samples with different HPV genotypes and high-grade lesions diagnosed based on cytology, histology, and colposcopy.

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