IGF-I

Developmental changes in IGF-I and MyoG gene expression and their association with meat traits in sheep

W. Sun, Su, R., Li, D., Musa, H. H., Kong, Y., Ding, J. T., Ma, Y. H., Chen, L., Zhang, Y. F., and Wu, W. Z., “Developmental changes in IGF-I and MyoG gene expression and their association with meat traits in sheep”, vol. 13, pp. 2772-2783, 2014.

In the present study, real time-polymerase chain reaction was applied to analyze the expression of IGF-I and MyoG genes in Hu sheep longissimus dorsi at different growth stages and their association with meat traits. Expression of the IGF-I gene in Hu sheep differed significantly between males and females at the two day-old (0.01 0.05) between males and females at any growth stage in expression of the MyoG gene. MyoG gene expression in male longissimus muscles tended to be higher than that of females at all growth stages, except for the six month-old stage.

Association between DLK1 and IGF-I gene expression and meat quality in sheep

R. Su, Sun, W., Li, D., Wang, Q. Z., Lv, X. Y., Musa, H. H., Chen, L., Zhang, Y. F., and Wu, W. Z., “Association between DLK1 and IGF-I gene expression and meat quality in sheep”, vol. 13, pp. 10308-10319, 2014.

The aim of the present study was to detect delta-like 1 ho­molog (DLK1) and insulin-like growth factor-I (IGF-I) gene expression in the longissimus dorsi of Hu sheep at different growth stages and study the association between these genes and meat quality. The diameter and density of muscle fibers and tenderness of the longissimus dorsi were measured. Growth stage, but not sex, significantly affected DLK1 and IGF-I expression.

Expression of growth genes in response to glycerol use in Japanese quail diets

E. Gasparino, Neto, A. R. Oliveira, Del Vesco, A. P., Pires, A. V., Batista, E., Voltolini, D. M., and Souza, K. R. S., “Expression of growth genes in response to glycerol use in Japanese quail diets”, vol. 11, pp. 3063-3068, 2012.

Glycerol can be used as a substitute for corn for feeding poultry, but there are concerns about how it may affect growth performance and health of the birds. We evaluated the expression of mRNA of growth hormone (GH) and insulin-like growth factor I (IGF-I) in 35-day-old Japanese quails fed different glycerol levels (0, 4, and 8% dietary glycerol instead of corn). Total RNA was extracted from the breast muscle and cDNA was amplified with the use of specific primers for these genes using real-time PCR.

Insulin-like growth factor I gene polymorphism associated with growth and carcass traits in Thai synthetic chickens

N. Promwatee, Laopaiboon, B., Vongpralub, T., Phasuk, Y., Kunhareang, S., Boonkum, W., and Duangjinda, M., “Insulin-like growth factor I gene polymorphism associated with growth and carcass traits in Thai synthetic chickens”, vol. 12, pp. 4332-4341, 2013.

Four Thai synthetic chicken lines (Kaen Thong, Khai Mook Esarn, Soi Nin, and Soi Pet) originated from Thai native and exotic commercial chickens were evaluated for their growth and carcass traits with the purpose of developing a Thai broiler breeding program. Insulin-like growth factor I (IGF-I) gene is known to play an important role in growth, proliferation and differentiation. Consequently, we investigated the possibility of using the IGF-I gene for marker-assisted selection in Thai synthetic chickens.

IGF-I gene polymorphism, but not its blood concentration, is associated with milk fat and protein in Holstein dairy cows

E. Bonakdar, Rahmani, H. R., Edriss, M. A., and Tabatabaei, B. E. Sayed, “IGF-I gene polymorphism, but not its blood concentration, is associated with milk fat and protein in Holstein dairy cows”, vol. 9, pp. 1726-1734, 2010.

We estimated the allele and genotype frequencies of IGF-I/SnaBI gene polymorphism and the concentration of this protein in Holstein dairy cows. We also examined the association with milk yield (305-day milk yield) and milk components (fat and protein percentage, and 305-day milk protein and fat yield). Blood IGF-I levels were measured and genotyping was performed on 250 Holstein cows of four different herds.

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