IL-10

Effect of compound Maqin decoction on TGF-β1/Smad proteins and IL-10 and IL-17 content in lung tissue of asthmatic rats

Y. H. Xie, Li, X. P., Xu, Z. X., Qian, P., Li, X. L., Wang, Y. Q., Xie, Y. H., Li, X. P., Xu, Z. X., Qian, P., Li, X. L., and Wang, Y. Q., Effect of compound Maqin decoction on TGF-β1/Smad proteins and IL-10 and IL-17 content in lung tissue of asthmatic rats, vol. 15, p. -, 2016.

In this research, compound Maqin decoction (CMD) has been shown to positively affect in airway inflammation of asthma models. We evaluated the effects of CMD on the expression of transforming growth factor (TGF)-β1/Smad proteins, interleukin (IL)-17, and IL-10 in lung tissue of asthmatic rats. Asthma was induced in a rat model using ovalbumin. After a 4-week treatment with CMD, rats were killed to evaluate the expression of TGF-β1 and Smad proteins in lung tissue. IL-10 and IL-17 levels in lung tissue homogenates were determined by ELISA.

Association between -1082G/A, -819C/T, and -592C/A genetic polymorphisms in IL-10 and risk of type 2 diabetes mellitus in a Chinese population

Q. Y. Dong, Liu, X. M., Liang, C. G., Du, W. H., Wang, Y. L., Li, W. X., Gao, G. Q., Dong, Q. Y., Liu, X. M., Liang, C. G., Du, W. H., Wang, Y. L., Li, W. X., and Gao, G. Q., Association between -1082G/A, -819C/T, and -592C/A genetic polymorphisms in IL-10 and risk of type 2 diabetes mellitus in a Chinese population, vol. 15, p. -, 2016.

Type 2 diabetes mellitus is the most common form of endocrine disease in humans; genetic factors are known to contribute to the development of this disease. In this case-control study, we investigated the relationship between the -1082G/A, -819C/T, and -592C/A polymorphisms in interleukin 10 (IL-10) and the pathogenesis of type 2 diabetes mellitus in a Chinese population.

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