IL-10 gene promoter

IL-10 promoter SNPs and susceptibility to leprosy in ethnic groups from southwest China

X. H. Chen, Xiong, J. H., Ning, Y., Wen, Y., Liu, J., Mao, C., Weng, X. M., and Gu, J. C., IL-10 promoter SNPs and susceptibility to leprosy in ethnic groups from southwest China, vol. 12, pp. 2876-2885, 2013.

The purpose of this study was to determine whether interleukin-10 (IL-10) promoter polymorphisms are associated with leprosy or their subtypes in ethnic groups from southwest China. Genotyping using TaqMan® SNP Genotyping Master Mix and ABI 7500 real-time PCR system was performed for IL-10 T3575A, G2849A, C2763A, A1082G, C819T, and C592A in 189 healthy controls (40 ± 18 years) and 193 patients (46 ± 18 years) with leprosy [multibacillary, N = 131; paucibacillary (PB), N = 62].

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