IL-18

Clinical significance of interleukin-4 and interleukin-18 levels in aggressive non-Hodgkin’s lymphoma patients

H. O. Soydinc, Guney, N., Basaran, M., Duranyildiz, D., Yasasever, V., Soydinc, H. O., Guney, N., Basaran, M., Duranyildiz, D., and Yasasever, V., Clinical significance of interleukin-4 and interleukin-18 levels in aggressive non-Hodgkin’s lymphoma patients, vol. 15, p. -, 2016.

Strong evidence indicates that tumor growth can be actively controlled by the immune system, and interleukins (ILs) are known to play an influential role in immune response regulation. Moreover, inflammatory cytokines are significantly involved in lymphoma pathogenesis. We aimed to investigate serum levels of IL-4 and IL-18 in aggressive non-Hodgkin’s lymphoma (A-NHL) patients and their relationship with prognostic parameters and therapy outcome.

Influence of interleukin-18 gene polymorphisms on acute pancreatitis susceptibility in a Chinese population

H. B. Gui, Du, X. G., Fu, Z. H., Chen, X. M., Gui, H. B., Du, X. G., Fu, Z. H., and Chen, X. M., Influence of interleukin-18 gene polymorphisms on acute pancreatitis susceptibility in a Chinese population, vol. 15, p. -, 2016.

We investigate the relationship between IL-18 -607C/A and -137G/C genetic polymorphisms and development of acute pancreatitis in a Chinese population. A total of 153 patients were consecutively recruited from the First Affiliated Hospital of Chongqing Medical University between January 2013 and November 2014. Genotyping of IL-18 -607C/A and -137G/C variants was performed using the polymerase chain reaction-restriction fragment length polymorphism method.

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