Inflammation

Lack of association between IL-10 -1082G/A polymorphism and chronic periodontal disease in adults

R. Hannum, Godoy, F. R., da Cruz, A. S., Vieira, T. C., Minasi, L. B., D. Silva, deM. e, da Silva, C. C., and da Cruz, A. D., Lack of association between IL-10 -1082G/A polymorphism and chronic periodontal disease in adults, vol. 14, pp. 17828-17833, 2015.

Because of the complex interaction between periodontal pathogens and the host defense system, periodontitis is considered an inflammatory disorder of bacterial etiology that results in periodontal tissue damage. Genetic mechanisms may interfere with the gene expression of important inflammation mediators, modulating the immunologic response of an individual. In this study, we evaluated the single nucleotide polymorphism -1082G/A in the promoter region of interleukin-10 gene and its relationship with periodontal disease in Central Brazil.

Protective effect and mechanism of probucol in the treatment of spinal cord injury

W. B. Zhu, Wang, Y. H., Sun, G. F., and Wu, J. H., Protective effect and mechanism of probucol in the treatment of spinal cord injury, vol. 14, pp. 8029-8037, 2015.

To investigate the effects of probucol on the treatment of spinal cord injury in rat, 80 rats were randomly divided into two groups of 40: a group treated with probucol and a control group. Allen’s method was used to establish a rat model of spinal cord injury. After establishment, probucol (500 mg·kg-1·day-1) was intraperitoneally injected into the treatment group rats for 1 week, while the same amount of saline was used to treat the control group.

Subscribe to Inflammation