Interaction network

Genome-wide identification, classification, and analysis of heat shock transcription factor family in Chinese cabbage (Brassica rapa pekinensis)

X. Y. Huang, Tao, P., Li, B. Y., Wang, W. H., Yue, Z. C., Lei, J. L., and Zhong, X. M., “Genome-wide identification, classification, and analysis of heat shock transcription factor family in Chinese cabbage (Brassica rapa pekinensis)”, vol. 14, pp. 2189-2204, 2015.

Chinese cabbage (Brassica rapa ssp. pekinensis) is one of the most important vegetable crops grown worldwide, and various methods exist for selection, propagation, and cultivation. The entire Chinese cabbage genome has been sequenced, and the heat shock transcription factor family (Hsfs) has been found to play a central role in plant growth and development and in the response to biotic and abiotic stress conditions, particularly in acquired thermotolerance. We analyzed heat tolerance mechanisms in Chinese cabbage.

Screening of differentially expressed genes between multiple trauma patients with and without sepsis

S. C. Ji, Pan, Y. T., Lu, Q. Y., Sun, Z. Y., and Liu, Y. Z., “Screening of differentially expressed genes between multiple trauma patients with and without sepsis”, vol. 13, pp. 1855-1864, 2014.

The purpose of this study was to identify critical genes associated with septic multiple trauma by comparing peripheral whole blood samples from multiple trauma patients with and without sepsis. A microarray data set was downloaded from the Gene Expression Omnibus (GEO) database. This data set included 70 samples, 36 from multiple trauma patients with sepsis and 34 from multiple trauma patients without sepsis (as a control set). The data were preprocessed, and differentially expressed genes (DEGs) were then screened for using packages of the R language.

Bioinformatic analysis of miRNA expression patterns in TFF2 knock-out mice

Y. Yin, Shan, H. Q., Huang, W., Wu, Y. M., Lu, H., and Jin, Y., “Bioinformatic analysis of miRNA expression patterns in TFF2 knock-out mice”, vol. 13, pp. 8502-8510, 2014.

Trefoil factors, which bear a unique 3-loop trefoil domain, are a family of small secretory protease-resistant peptides (7-12 kDa) discovered in the 1980s. Trefoil factor 2 (TFF2) is a unique member of trefoil factors family that plays important roles in gastrointestinal mucosal defense and repair. However, few studies have characterized the miRNA expression patterns in TFF2 knock-out mice. In this study, we investigated the regulatory role of miRNAs in TFF2 knock-out mice.

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