Interleukin

Immunomodulatory and clinical effects of the "tiaomian III decoction" in patients with blood blocking antibody deficiency and recurrent spontaneous abortion

H. Y. Gao, Tao, E. X., Wang, Y., Yue, Q. A., Ren, C. E., and Yan, L. F., Immunomodulatory and clinical effects of the "tiaomian III decoction" in patients with blood blocking antibody deficiency and recurrent spontaneous abortion, vol. 14, pp. 3421-3425, 2015.

We studied the immunomodulatory and clinical effects of the empirical formula "tiaomian III decoction" on maternal blood blocking antibody deficiency and recurrent spontaneous abortion. Sixty-one patients with blocking antibody deficiency were divided in the experimental group (N = 31), who took tiaomian III decoction, and the control group (N = 30), who received active immunotherapy with paternal lymphocytes; both treatments lasted 3 months.

PPAR-γ agonist pioglitazone affects rat gouty arthritis by regulating cytokines

R. - C. Wang and Jiang, D. - M., PPAR-γ agonist pioglitazone affects rat gouty arthritis by regulating cytokines, vol. 13, pp. 6577-6581, 2014.

The objective was to study peroxisome proliferator-activated receptor gamma (PPARγ) agonist pioglitazone regulation effect and its mechanism of expression of cytokines on acute gouty arthritis synovial in rats. Rats with unilateral ankle were injected with artificial monosodium urate (MSU) crystals to make the acute gouty arthritis model.

Association of variable number of tandem repeats polymorphism in the IL-4 gene with end-stage renal disease in Malaysian patients

R. Vasudevan, Norhasniza, M. N., and Patimah, I., Association of variable number of tandem repeats polymorphism in the IL-4 gene with end-stage renal disease in Malaysian patients, vol. 10, pp. 943-947, 2011.

Variable number of tandem repeats (VNTR) polymorphism in the interleukin 4 (IL-4) gene has been associated with end-stage renal disease (ESRD) subjects in many different populations, although with conflicting results. We determined the 70 bp of VNTR polymorphism at intron 3 of the IL-4 gene in Malaysian ESRD subjects. Buccal cells were collected from 160 case and 160 control subjects; genomic DNA was amplified using PCR, followed by agarose gel electrophoresis. There were significant differences in genotypes and alleles of the IL-4 gene.

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