Expression and effect of serum interleukin-24 level on bone marrow mononuclear cells in children with acute leukemia
“Expression and effect of serum interleukin-24 level on bone marrow mononuclear cells in children with acute leukemia”, vol. 14, pp. 17281-17288, 2015.
, To investigate the expression of interleukin-24 (IL-24) in the children with acute leukemia (AL) and its effect on the apoptosis of bone marrow mononuclear cells (BMMNCs) in vitro. Four groups were assessed: acute lymphocytic leukemia (ALL), acute myeloid leukemia (AML), non-leukemia, and healthy groups, 20 children in each group. ELISA was used to measure IL-24 serum level. The bone marrow was taken from patients and controls. BMMNCs were isolated and the DNA was analyzed by glucose electrophoresis. Flow cytometry was used to determine BMMNC apoptosis.