Pivotal role of microRNA-9 in osteosarcoma tumorigenesis and tumor progression
“Pivotal role of microRNA-9 in osteosarcoma tumorigenesis and tumor progression”, vol. 15, p. -, 2016.
, MicroRNA-9 (miR-9) has a well-established role in various tumors; the clinical significance and potential mechanism of miR-9 in human osteosarcoma (OS) has not been elucidated. The aim of this study was to investigate the mechanism and role of miR-9 expression in osteosarcoma cells. miR-9 expression in the OS cell line MG-63 and OS tissues was compared to that in a human osteoblastic cell line (hFOB 1.19) and adjacent normal tissues, respectively, by reverse transcriptase-polymerase chain reaction.