Ischemic stroke

Association of the interleukin-10 gene -1082A/G genetic polymorphism with risk of ischemic stroke in a Chinese population

W. Z. Li, Gao, C. Y., He, W. L., Zhang, H. M., Li, W. Z., Gao, C. Y., He, W. L., Zhang, H. M., Li, W. Z., Gao, C. Y., He, W. L., and Zhang, H. M., Association of the interleukin-10 gene -1082A/G genetic polymorphism with risk of ischemic stroke in a Chinese population, vol. 15, p. -, 2016.

We investigated the possible association between two single nucleotide polymorphisms of IL10 (-1082A/G and -592C/A) and susceptibility to ischemic stroke. In total, 335 patients with proven ischemic stroke and 335 control subjects were recruited from Xinxiang Central Hospital between March 2013 and May 2015. The IL10 -1082A/G and -529C/A polymorphisms were investigated by polymerase chain reaction-restriction fragment length polymorphism.

Association between the interleukin-6-174 G/C polymorphism and risk of ischemic stroke: a meta-analysis

X. F. Jin, Wang, D. L., Zhou, Y., and Xiong, H., Association between the interleukin-6-174 G/C polymorphism and risk of ischemic stroke: a meta-analysis, vol. 14, pp. 13076-13083, 2015.

Numerous studies have evaluated the association between the -174 G/C polymorphism in the interleukin-6 (IL6) gene and ischemic stroke risk. However, the results have been inconsistent. In this study, we performed a meta-analysis to assess the association of the IL6 -174 G/C polymorphism with ischemic stroke. Published literatures from PubMed and Embase databases were retrieved. Pooled ORs with 95%CIs were calculated using fixed- or random-effect models.

 Investigation of single nucleotide polymorphisms in phosphodiesterase 4D gene in Mongol and Han patients with ischemic stroke in Inner Mongolia

J. P. Shi, Chen, W. D., Zhou, J. Q., Xue, M. M., Xue, F., Li, H. Z., and Xu, Z. P.,  Investigation of single nucleotide polymorphisms in phosphodiesterase 4D gene in Mongol and Han patients with ischemic stroke in Inner Mongolia, vol. 14, pp. 10281-10287, 2015.

We investigated single nucleotide polymorphisms (SNP) at 87 sites of the phosphodiesterase 4D (PDE4D) gene in Mongol and Han patients with ischemic stroke in Inner Mongolia. SNPs in 226 patients with ischemic stroke (case group, 110 Mongol patients, 116 Han patients) and 220 patients without neurological disease (control group, 102 Mongol patients, 118 Han patients) were detected by polymerase chain reaction-restriction fragment length polymorphism and gene sequencing. The genotype and allele frequencies of all groups were compared.

Subscribe to Ischemic stroke