Isolated hypospadias

Androgen receptor gene CAG repeat polymorphism and risk of isolated hypospadias: results from a meta-analysis

G. Huang, Shan, W., Zeng, L., and Huang, L., Androgen receptor gene CAG repeat polymorphism and risk of isolated hypospadias: results from a meta-analysis, vol. 14, pp. 1580-1588, 2015.

Studies investigating the association between the CAG repeat polymorphism and the risk of isolated hypospadias have reported conflicting results. The aim of this study was to quantitatively summarize the evidence for such a relationship. Two investigators independently searched the Medline, Embase, CNKI, and Wanfang databases. Weighted mean difference and 95% confidence intervals for the CAG repeat polymorphism and isolated hypospadias were calculated using a random-effects model.

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