Malaysia

Association between the C34T polymorphism of the AMPD1 gene and essential hypertension in Malaysian patients

R. Nemati, Lu, J., Ramachandran, V., Etemad, A., Heidari, M., Yahya, M. J., Roozafzoon, R., Ismail, P., Nemati, R., Lu, J., Ramachandran, V., Etemad, A., Heidari, M., Yahya, M. J., Roozafzoon, R., and Ismail, P., Association between the C34T polymorphism of the AMPD1 gene and essential hypertension in Malaysian patients, vol. 15, p. -, 2016.

The aim of this study was to determine whether C34T, a common polymorphism of the adenosine monophosphate deaminase 1 gene (AMPD1), is associated with essential hypertension (EH). We hypothesize that C34T is associated with the development of EH. A case-control design was used for this study. The DNA was extracted using a commercial kit from the whole blood of 200 patients with hypertension and 200 subjects without hypertension from selected Malaysian ethnicities (Malays, Chinese, and Indians).

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