Male infertility

Correlation between chromosomal polymorphisms and male infertility in a Northeast Chinese population

L. L. Li, Peng, D., Wang, R. X., Zhu, H. B., Wang, W. J., and Liu, R. Z., Correlation between chromosomal polymorphisms and male infertility in a Northeast Chinese population, vol. 14, pp. 15435-15443, 2015.

The aim of this study was to evaluate the correlation between chromosomal polymorphisms and male infertility. The patients were diagnosed with azoospermia or oligospermiaby a semen analysis. Chromosomal analysis was performed on peripheral blood lymphocytes obtained from the patients, with standard G-banding and C-banding. Y chromosome microdeletions were detected by multiplex polymerase chain reaction (PCR) amplification. The parents of 35 polymorphic probands were also subjected to chromosomal analysis, and their detailed reproductive histories were surveyed.

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