Lack of association between MD-2 promoter gene variants and tuberculosis
, “Lack of association between MD-2 promoter gene variants and tuberculosis”, vol. 9, pp. 1584-1590, 2010.
Myeloid differentiation-2 (MD-2) is an essential component of the CD14-TLR4/MD-2 receptor complex involved in microbial cell wall component recognition during infection. Genetic variations in the MD-2 gene may influence human susceptibility to infectious diseases. To date, a predisposition of MD-2 gene variants to contract tuberculosis has not been reported. We investigated whether MD-2 gene polymorphisms were associated with the development of tuberculosis in a Chinese population.
