Medulloblastoma

Isolation and characterization of cancer stem cells from medulloblastoma

J. Liu, Chi, N., Zhang, J. Y., Zhu, W., Bian, Y. S., and Chen, H. G., Isolation and characterization of cancer stem cells from medulloblastoma, vol. 14, pp. 3355-3361, 2015.

Brain cancer stem cells are a subset of tumor cells present in several types of brain tumor that evade treatment regimens and are responsible for tumor recurrence. Recent reports on several tumors have suggested that Hoechst 33342 dye exclusion is a powerful technique for isolating cancer stem cell-like side population (SP) cells. In the present study, we attempted to isolate the SP cells from medulloblastoma, a malignant brain tumor in children. The tumor samples obtained were subjected to fluorescence-activated cell sorting analysis for SP cell isolation.

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