Meta-analysis

Association between IL-21 polymorphism and systemic lupus erythematosus: a meta-analysis

J. H. Qi, Qi, J., Xiang, L. N., and Nie, G., Association between IL-21 polymorphism and systemic lupus erythematosus: a meta-analysis, vol. 14, pp. 9595-9603, 2015.

Several case-control studies have been conducted to investigate the association between Interleukin-21 (IL-21) polymorphisms and systemic lupus erythematosus (SLE) susceptibility, and most of the studies focused on IL-21 rs907715 and rs2221903 polymorphisms. Given the inconsistent results from these studies, the present meta-analysis aimed to obtain a more precise estimate of the association between IL-21 rs907715 and rs2221903 polymorphisms and SLE. Studies regarding these specific polymorphisms and SLE were retrieved from PubMed, Embase, Web of Science, CNKI, and CBM.

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