Migration

miR-133 inhibits pituitary tumor cell migration and invasion via down-regulating FOXC1 expression

D. S. Wang, Zhang, H. Q., Zhang, B., Yuan, Z. B., Yu, Z. K., Yang, T., Zhang, S. Q., Liu, Y., Jia, X. X., Wang, D. S., Zhang, H. Q., Zhang, B., Yuan, Z. B., Yu, Z. K., Yang, T., Zhang, S. Q., Liu, Y., Jia, X. X., Wang, D. S., Zhang, H. Q., Zhang, B., Yuan, Z. B., Yu, Z. K., Yang, T., Zhang, S. Q., Liu, Y., and Jia, X. X., miR-133 inhibits pituitary tumor cell migration and invasion via down-regulating FOXC1 expression, vol. 15, p. -, 2016.

Many studies have shown that microRNA (miR)-133 functions as a tumor suppressor in a variety of metastatic cancers, including breast cancer, gastric cancer, and liver fibrosis. However, the influence of miR-133 on pituitary tumor malignancy has not yet been reported. The purpose of this study was to explore the role of miR-133 in pituitary tumor cell migration and invasive ability and the molecular mechanisms involved.

Role of adiponectin in adipose tissue wound healing

C. E. Jin, Xiao, L., Ge, Z. H., Zhan, X. B., and Zhou, H. X., Role of adiponectin in adipose tissue wound healing, vol. 14, pp. 8883-8891, 2015.

The purpose of this study was to investigate the mechanism behind adipose tissue wound healing (ATWH). The preadipocyte cell line 3T3-L1 was cultured and expression of adiponectin receptors (AdipoR1/2) was detected by immunohistochemistry and reverse transcription polymerase chain reaction. The concentration of adiponectin secreted at different cell densities was measured by enzyme-linked immunosorbent assay, while preadipocyte proliferation and migration were determined in vitro by MTT and wound closure assays. AdipoR1/2 were found to be expressed in 3T3-L1 preadipocytes.

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