Milk traits

Association of novel single nucleotide polymorphisms of the CXCR1 gene with the milk performance traits of Chinese native cattle

L. Zhou, Wang, H. M., Ju, Z. H., Zhang, Y., Huang, J. M., Qi, C., Hou, M. H., An, L. G., Zhong, J. F., and Wang, C. F., Association of novel single nucleotide polymorphisms of the CXCR1 gene with the milk performance traits of Chinese native cattle, vol. 12, pp. 2725-2739, 2013.

Mastitis is an economically devastating disease affecting the dairy industry. Dairy cows with mastitis give reduced milk yield and produce milk that is unfit for consumption. The chemokine receptor CXCR1 is an excellent prospective genetic marker for mastitis resistance in cattle because it regulates neutrophil migration, killing, and survival during infection. We detected 4 single nucleotide polymorphisms (SNPs) of the CXCR1 gene in Chinese native cattle and analyzed their associations with milk traits.

AGPAT6 polymorphism and its association with milk traits of dairy goats

C. He, Wang, C., Chang, Z. H., Guo, B. L., Li, R., Yue, X. P., Lan, X. Y., Chen, H., and Lei, C. Z., AGPAT6 polymorphism and its association with milk traits of dairy goats, vol. 10, pp. 2747-2756, 2011.

As one of the eight members in the 1-acylglycerol-3-phosphate-O-acyltransferase (AGPATs) family, AGPAT6 is a crucial enzyme for the biosynthesis of glycerolipids and triacylglycerol in eukaryotes, as well as catalyzing the conversion from lysophosphatidic acid to phosphatidic acid. AGPAT6 can be considered as a candidate gene for regulating milk composition. DNA sequencing and PCR-RFLP methods were applied to detect genetic variation in the AGPAT6 gene in 549 Chinese dairy goats.

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