Analysis of GATA1 mutations and leukemogenesis in newborns with Down syndrome
“Analysis of GATA1 mutations and leukemogenesis in newborns with Down syndrome”, vol. 12, pp. 4630-4638, 2013.
, It has been reported that patients with Down syndrome (DS) frequently develop transient myeloproliferative disorder (TMD) and less commonly myeloid leukemia in DS (ML-DS). We examined the pathogenetic relationship of these conditions with somatic mutations of the GATA1 gene in children with both TMD and ML-DS.