miR-21

Investigation of the value of miR-21 in the diagnosis of early stage HCC and its prognosis: a meta-analysis

S. R. Yan, Liu, Z. J., Yu, S., and Bao, Y. X., Investigation of the value of miR-21 in the diagnosis of early stage HCC and its prognosis: a meta-analysis, vol. 14, pp. 11573-11586, 2015.

The diagnostic and prognostic value of miR-21 has been examined for hepatocellular carcinoma (HCC), with inconsistent results. Present meta-analysis summarized the diagnostic accuracy and the predictive role for survival of miR-21 in patients with HCC. All eligible studies were searched using PubMed, EMBASE, and Chinese National Knowledge Infrastructure (CNKI) databases up to October 2014. For the diagnostic meta-analysis, the indices of miR-21 in the diagnosis of HCC were pooled using bivariate random-effect approach models.

Association of miR-21 with esophageal cancer prognosis: a meta-analysis

S. - W. Wen, Zhang, Y. - F., Li, Y., Liu, Z. - X., Lv, H. - L., Li, Z. - H., Xu, Y. - Z., Zhu, Y. - G., and Tian, Z. - Q., Association of miR-21 with esophageal cancer prognosis: a meta-analysis, vol. 14, pp. 6578-6582, 2015.

The present study aimed to explore the relationship between miRNA expression and survival in patients with esophageal cancer (EC) using meta-analysis. We searched PubMed, EMBASE, CNKI, Wanfang, and ISI Web of Science databases without time restrictions, and extracted relevant data, such as the name of first author, publication year, age, gender, number of case, etc. from the studies included. We calculated the pooled hazard ratios (HRs) using the RevMan 5.2 software.

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