Mitochondrial ATP-sensitive potassium channel

Effect of mitochondrial ATP-sensitive potassium channel opening on the translocation of protein kinase C epsilon in adult rat ventricular myocytes

H. Li, Yang, T., Long, Z., and Cheng, J., Effect of mitochondrial ATP-sensitive potassium channel opening on the translocation of protein kinase C epsilon in adult rat ventricular myocytes, vol. 13, pp. 4516-4522, 2014.

This study aimed to investigate the effects of mitochondrial ATP-sensitive potassium (MitoKATP) channel opening on the translocation of protein kinase C epsilon (PKCε). In addition, we aimed to determine the relationship between PKCε translocation and the production of reactive oxygen species (ROS). PKCε protein expression in cultured adult rat ventricular myocytes was investigated by immunofluorescence and Western blotting.

Cardioprotective effects mitochondrial ATP-sensitive potassium channel in exercise conditioning

F. - L. Peng, Guo, Y. - J., Mo, W. - B., Xu, S. - M., and Liao, H. - P., Cardioprotective effects mitochondrial ATP-sensitive potassium channel in exercise conditioning, vol. 13, pp. 7503-7512, 2014.

We investigated the mitochondrial ATP-sensitive potassium channel [mito-K (ATP)] in exercise preconditioning of myocardial ischemia-reperfusion injury in rats. Eighty SD rats were randomly divided into high-, moderate-, low-intensity, and control groups. The exercise groups were divided into control and inhibited groups. The control group was divided into model and sham groups. Eight rats were randomly selected from each group for analysis.

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