MicroRNA-122 is involved in oxidative stress in isoniazid-induced liver injury in mice
“MicroRNA-122 is involved in oxidative stress in isoniazid-induced liver injury in mice”, vol. 14, pp. 13258-13265, 2015.,
Many studies have shown that the pathogenesis of liver injury includes oxidative stress. MicroRNA-122 may be a marker for the early diagnosis of drug-induced liver injury. However, the relationship between microRNA-122 and oxidative stress in anti-tuberculosis drug-induced liver injury remains unknown. We measured changes in tissue microRNA-122 levels and indices of oxidative stress during liver injury in mice after administration of isoniazid, a first-line anti-tuberculosis drug.