MK-801

Effects of MK-801 concentration on cell proliferation in rats with focal cerebral ischemia-reperfusion

Y. K. Gui, Su, L. L., Niu, X. L., Zeng, P., Fang, R. R., Lv, H. X., and Zhang, P., Effects of MK-801 concentration on cell proliferation in rats with focal cerebral ischemia-reperfusion, vol. 14, pp. 12841-12847, 2015.

We explored the relationship between MK-801 concentration and neural stem cell proliferation in rats with focal cerebral ischemia-reperfusion (FCIR). A total of 60 male Sprague Dawley rats were randomized into control (six rats), sham-operation (six rats), operation (12 rats), and MK-801 groups. The MK-801 group comprised 36 rats that were subjected to different doses of MK-801 (0.2, 0.4, 0.6, 0.8, 1.0, and 1.2 mg/kg).

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