MKL1-184C>T gene polymorphism is associated with coronary artery disease in the Chinese Han population
“MKL1-184C>T gene polymorphism is associated with coronary artery disease in the Chinese Han population”, vol. 13, pp. 590-597, 2014.
, We investigated genetic susceptibility to coronary artery disease (CAD) by studying the association of MKL1 gene polymorphisms with CAD in the Chinese Han population. We performed a case-control study with 476 unrelated CAD patients and 325 non-CAD controls. All SNPs were genotyped with a TaqMan SNP genotyping assay. The distribution of MKL1-184C>T gene polymorphism in each group was in Hardy-Weinberg equilibrium. The frequency of the MKL1 T allele in the CAD group was significantly higher than in the control group (38.6 vs 30.8%).