MMP-8

Regulating effect of MMP-9 and TIMP-1 in pi­tuitary adenoma invasion

J. H. Mao, Guo, H., Si, N., Qiu, L., Guo, L. F., Sun, Z. S., Xiang, Y., Yang, X. H., Zhao, W. G., and Zhang, W. C., Regulating effect of MMP-9 and TIMP-1 in pi­tuitary adenoma invasion, vol. 14, pp. 17091-17098, 2015.

Pituitary adenomas can cause endocrine disorder and organ damage, with some aggressive ones leading to a high postoperative recurrence rate. The occurrence and development of these type of tumors is closely related with matrix metalloproteinases (MMPs) and endogenous specific tissue inhibitor of MMPs (TIMPs). In this study, the relationship between pituitary adenoma invasion and the changes in MMP-8 and TIMP-1 expressions is analyzed.

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