Myocardial apoptosis

Effect of hydroxy safflower yellow A on myocardial apoptosis after acute myocardial infarction in rats

M. X. Zhou, Fu, J. H., Zhang, Q., and Wang, J. Q., Effect of hydroxy safflower yellow A on myocardial apoptosis after acute myocardial infarction in rats, vol. 14, pp. 3133-3141, 2015.

This study aimed to investigate the effect of hydroxy safflower yellow A (HSYA) on myocardial apoptosis after acute myocardial infarction (AMI) in rats. We randomly divided 170 male Wistar rats into 6 groups (N = 23): normal control, sham, control, SY (90 mg/kg), HSYA high-dose (HSYA-H, 40 mg/kg), and HSYA low-dose groups (HSYA-L, 20 mg/kg). Myocardial ischemic injury was induced by ligating the anterior descending coronary artery, and the degree of myocardial ischemia was evaluated using electrocardiography and nitroblue tetrazolium staining.

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