Neonatal bull

In vitro differentiation of sperm from male germline stem cell

P. Zheng, Zhao, X. W., Zheng, X. M., Khalid, A., Zhao, Q., and Zhang, G. X., In vitro differentiation of sperm from male germline stem cell, vol. 14, pp. 2964-2969, 2015.

In this study, we developed a model of sperm in vitro differentiation to study the mechanism of spermatogenesis. We isolated newborn male germ cells for in vitro differentiation. We found that after 4-5 weeks of culture, sperm-like cells were occasionally observed in cell co-culture and the feed-layer. After 1-2 weeks of culture followed by 4-5 weeks of co-culture, sperm-like cells were observed.

Subscribe to Neonatal bull