Embolus-carried vascular endothelial cell growth factor 165 improves angiogenesis in thromboangiitis obliterans
“Embolus-carried vascular endothelial cell growth factor 165 improves angiogenesis in thromboangiitis obliterans”, vol. 13, pp. 1744-1752, 2014.
, We investigated neovasculization effects of embolus-carried human vascular endothelial cell growth factor 165 (VEGF165)-encoded adenovirus (Ad) vector in the hindlimbs of rats with thromboangiitis obliterans (TAO). Rats were equally divided into blank control (I), TAO model (II), embolus (III), Ad-VEGF165 intravascular treatment (IV), Ad-VEGF165 intramuscular treatment (V), and embolus-carried Ad-VEGF165 (VI) groups. After interventional treatment, the neovasculization effect of the test gene was observed using immunohistochemistry.