Neovascularization

Embolus-carried vascular endothelial cell growth factor 165 improves angiogenesis in thromboangiitis obliterans

Q. Liu, Zhou, H. C., Yang, X. L., Zhao, Y. P., Luo, H. P., He, C. W., and Wan, X. B., Embolus-carried vascular endothelial cell growth factor 165 improves angiogenesis in thromboangiitis obliterans, vol. 13, pp. 1744-1752, 2014.

We investigated neovasculization effects of embolus-carried human vascular endothelial cell growth factor 165 (VEGF165)-encoded adenovirus (Ad) vector in the hindlimbs of rats with thromboangiitis obliterans (TAO). Rats were equally divided into blank control (I), TAO model (II), embolus (III), Ad-VEGF165 intravascular treatment (IV), Ad-VEGF165 intramuscular treatment (V), and embolus-carried Ad-VEGF165 (VI) groups. After interventional treatment, the neovasculization effect of the test gene was observed using immunohistochemistry.

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