Neural regeneration

Tetradecyl 2,3-dihydroxybenzoate promotes functional recovery after spinal cord injury in adult rats

Y. M. Ding, Zhu, J. Y., Zhang, S. J., Zhang, S. S., Wang, C., Wang, L. L., Zhang, X., Ding, Y. M., Zhu, J. Y., Zhang, S. J., Zhang, S. S., Wang, C., Wang, L. L., and Zhang, X., Tetradecyl 2,3-dihydroxybenzoate promotes functional recovery after spinal cord injury in adult rats, vol. 15, p. -, 2016.

Tetradecyl 2,3-dihydroxybenzoate (ABG001) is a small molecule separated from gentian extract that has a similar effect to nerve growth factor. It is not clear whether it can promote functional recovery in animals suffering from a central nervous system injury. In order to explore the role of ABG001 in restoration of tissue structure and motor function of rats with spinal cord injury (SCI), ABG001 (0.4 mg/kg) was administered intraperitoneally.

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