Nonstructural protein

Efficacy of Artemisia annua polysaccharides as an adjuvant to hepatitis C vaccination

L. D. Bao, Ren, X. H., Ma, R. L., Wang, Y., Yuan, H. W., and Lv, H. J., Efficacy of Artemisia annua polysaccharides as an adjuvant to hepatitis C vaccination, vol. 14, pp. 4957-4965, 2015.

The traditional Chinese medicine Artemisia annua can prevent and treat hepatitis following an unclear mechanism. The aim of this study was to evaluate the effects of A. annua polysaccharides (AAP) on hepatitis C virus (HCV). A pcDNA3.1/NS3 expression vector was constructed. Ninety female BALB/c mice were randomly divided into six groups: high-dose AAP (1 mg/mL) + HCV/NS3 plasmid; middle-dose AAP (0.5 mg/mL) + HCV/NS3 plasmid; low-dose AAP (0.1 mg/mL) + HCV/NS3 plasmid; HCV/NS3 plasmid; high-dose AAP (1 mg/mL); normal saline control (N = 15).

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