Association of NPRA and NPRC gene variants and hypertension in Mongolian population
, “Association of NPRA and NPRC gene variants and hypertension in Mongolian population”, vol. 14, pp. 18494-18502, 2015.
NPRA and NPRC are candidate susceptibility genes for essential hypertension (EH) and play a key role in the regulation of plasma levels and biological effects of natriuretic peptides. The aims of the present study were to find new genetic markers in the NPRA and NPRC genes and to assess relationships between variants and EH. A total of 797 unrelated Mongolian herdsmen were enrolled, including 389 EH patients and 408 normotensive controls. Genotyping was performed using the polymerase chain reaction/ligase detection reaction assay.
