Obesity

Prevalence of mutations in LEP, LEPR, and MC4R genes in individuals with severe obesity

B. Paolini, Maltese, P. E., Del Ciondolo, I., Tavian, D., Missaglia, S., Ciuoli, C., Zuntini, M., Cecchin, S., Bertelli, M., Pompucci, G., Paolini, B., Maltese, P. E., Del Ciondolo, I., Tavian, D., Missaglia, S., Ciuoli, C., Zuntini, M., Cecchin, S., Bertelli, M., and Pompucci, G., Prevalence of mutations in LEP, LEPR, and MC4R genes in individuals with severe obesity, vol. 15, p. -, 2016.

Obesity is a major public health concern; despite evidence of high heritability, the genetic causes of obesity remain unclear. In this study, we assessed the presence of mutations in three genes involved in the hypothalamic leptin-melanocortin regulation pathway (leptin, LEP; leptin receptor, LEPR; and melanocortin-4 receptor, MC4R), which is important for energy homeostasis in the body, in a group of patients with severe obesity.

Exome sequencing in Thai patients with familial obesity

S. Kaewsutthi, Santiprabhob, J., Phonrat, B., Tungtrongchitr, A., Lertrit, P., Tungtrongchitr, R., Kaewsutthi, S., Santiprabhob, J., Phonrat, B., Tungtrongchitr, A., Lertrit, P., and Tungtrongchitr, R., Exome sequencing in Thai patients with familial obesity, vol. 15, p. -, 2016.

Obesity is a major worldwide health issue, with increasing prevalence in adults and children from developed and developing countries. Obesity causes several chronic diseases, including cardiovascular and respiratory diseases, osteoarthritis, hypertension, stroke, type II diabetes, obstructive sleep apnea, and several types of cancer.

Exome sequencing in Thai patients with familial obesity

S. Kaewsutthi, Santiprabhob, J., Phonrat, B., Tungtrongchitr, A., Lertrit, P., and Tungtrongchitr, R., Exome sequencing in Thai patients with familial obesity, vol. 15, p. -, 2016.

Obesity is a major worldwide health issue, with increasing prevalence in adults and children from developed and developing countries. Obesity causes several chronic diseases, including cardiovascular and respiratory diseases, osteoarthritis, hypertension, stroke, type II diabetes, obstructive sleep apnea, and several types of cancer.

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