Association of c.461G>A genetic variant of OGG1 gene with pancreatic cancer susceptibility in Chinese
“Association of c.461G>A genetic variant of OGG1 gene with pancreatic cancer susceptibility in Chinese”, vol. 13, pp. 7256-7261, 2014.
, This study aimed to evaluate the potential association of single nucleotide polymorphisms of the 8-oxoguanine DNA glycosylase gene (OGG1) with susceptibility to pancreatic cancer (PC). A total of 764 Chinese Han subjects were recruited in this study. The polymerase chain reaction-restriction fragment length polymorphism and DNA sequencing methods were used to detect the genotype of c.461G>A genetic variant of OGG1. The genotype and allele frequencies were statistically different in PC patients compared with cancer-free controls.