Oocyte

Exceptional material requirement for reproduction in mouse oocytes

L. Yu, Wang, S. F., Zhai, Q. Z., Yao, Y. Q., Jiang, F., and Lu, Y. X., Exceptional material requirement for reproduction in mouse oocytes, vol. 14, pp. 14356-14365, 2015.

Limited information on oocytes and fertilization prevents the efficient therapy of patients with infertility. The most important reason for this lack of understanding is a deficiency in research dedicated to oocytes and fertilization. Currently, we are concerned with the role of nutrition in the process of oocyte development to better understand the relationship between nutrition and infertility. The aim of this study was to explore the relationship between some exceptional materials and infertility to elucidate the role of these materials in oocyte development.

Expression pattern of JMJD1C in oocytes and its impact on early embryonic development

C. H. Li, Gao, Y., Wang, S., Xu, F. F., Dai, L. S., Jiang, H., Yu, X. F., Chen, C. Z., Yuan, B., and Zhang, J. B., Expression pattern of JMJD1C in oocytes and its impact on early embryonic development, vol. 14, pp. 18249-18258, 2015.

Cell reprogramming mediated by histone methylation and demethylation is crucial for the activation of the embryonic genome in early embryonic development. In this study, we employed quantitative real-time polymerase chain reaction (qRT-PCR) to detect mRNA levels and expression patterns of all known histone demethylases in early germinal vesicle stage and in vitro-matured metaphase II (MII) oocytes (which are commonly used as donor cells for nuclear transfer).

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