ORMDL3 gene

ORMDL3 variants associated with bronchiolitis susceptibility in a Chinese population

X. T. Liu, Ren, L., Zhou, L. L., Xiao, Q. Y., Deng, Y., and Liu, E. M., ORMDL3 variants associated with bronchiolitis susceptibility in a Chinese population, vol. 14, pp. 19155-19162, 2015.

Recent studies revealed common genetic risks for both viral bronchiolitis and asthma. Genome-wide association studies revealed that rs7216389 in the ORMDL3 gene is associated with childhood asthma. We conducted a case-control study examining the associations between ORMDL3 polymorphisms (rs7216389, rs12603332, and rs11650680) and bronchiolitis susceptibility/viral findings among 247 infant bronchiolitis cases and 190 healthy controls.

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